Prescribing patterns across four timepoints
| BNF category | Variable | Timepoint | N | Min. | Max. | Mean | SD | Statistically significant changes* | Statistically significant pairwise comparisons** |
|---|---|---|---|---|---|---|---|---|---|
| Total regularly prescribed medications | Number of medications | T1 (Admission) | 36 | 0 | 7 | 2.6 | 1.9 | ||
| T2 (Discharge) | 36 | 0 | 6 | 2.3 | 1.4 | ||||
| T3 (6 months post-discharge) | 36 | 0 | 5 | 1.9 | 1.3 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 4 | 1.7 | 1.3 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 378.3 | 127.1 | 98.9 | |||
| T2 (Discharge) | 36 | 0 | 387.5 | 121.2 | 97 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 307.1 | 101.4 | 80.2 | ||||
| T4 (12 months post-discharge) | 30 | 0 | 350 | 90.1 | 102.9 | ||||
| Regularly prescribed antipsychotic medications | Number of medications | T1 (Admission) | 35 | 0 | 3 | 0.7 | 0.8 | ||
| T2 (Discharge) | 36 | 0 | 2 | 0.8 | 0.6 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.8 | 0.6 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 2 | 0.8 | 0.7 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 168.8 | 27.1 | 41.8 | |||
| T2 (Discharge) | 36 | 0 | 143.3 | 38.9 | 37.6 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 141.7 | 33.5 | 37.3 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 140 | 31.7 | 37.9 | ||||
| Regularly prescribed mood stabilising medications | Number of medications | T1 (Admission) | 35 | 0 | 2 | 0.3 | 0.6 | F(1.928, 57.841) = 4.163, p = 0.022 | |
| T2 (Discharge) | 36 | 0 | 2 | 0.1 | 0.4 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.1 | 0.4 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 1 | 0.1 | 0.2 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 100 | 8.1 | 21.9 | |||
| T2 (Discharge) | 36 | 0 | 136 | 5 | 23.1 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 136 | 7.5 | 26.6 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 80 | 3.3 | 14.7 | ||||
| Regularly prescribed antidepressant medications | Number of medications | T1 (Admission) | 35 | 0 | 1 | 0.6 | 0.5 | ||
| T2 (Discharge) | 36 | 0 | 1 | 0.4 | 0.5 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 1 | 0.4 | 0.5 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 1 | 0.4 | 0.5 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 100 | 29.3 | 34.7 | |||
| T2 (Discharge) | 36 | 0 | 100 | 27.8 | 38.7 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 100 | 28.8 | 40.9 | ||||
| T4 (12 months post-discharge) | 31 | 0 | 100 | 23.9 | 37.9 | ||||
| Regularly prescribed anxiolytic and hypnotic medications | Number of medications | T1 (Admission) | 35 | 0 | 2 | 0.9 | 0.8 | F(2.304, 69.107) = 3.697, p = 0.025 | T1-T4 0.452 (95% CI, 0.001 to 0.902), p = 0.049 |
| T2 (Discharge) | 36 | 0 | 3 | 0.8 | 0.9 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.6 | 0.7 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 2 | 0.4 | 0.7 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 150 | 51.9 | 56.1 | |||
| T2 (Discharge) | 36 | 0 | 237.5 | 46.7 | 65.2 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 150 | 28.7 | 44 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 200 | 27.9 | 55.8 | ||||
| Other regularly prescribed psychotropic medications | Number of medications | T1 (Admission) | 35 | 0 | 1 | 0.2 | 0.4 | ||
| T2 (Discharge) | 36 | 0 | 1 | 0.1 | 0.3 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 1 | 0.1 | 0.3 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 1 | 0.1 | 0.3 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 50 | 5.2 | 12.6 | F(1.037, 29.044) = 19.822, p < 0.001 | T1-T4 85.817 (95% CI, 30.80 to 140.834), p = 0.001 T2-T4 86.966 (95% CI, 32.550 to 141.382), p = 0.001 T3-T4 86.966 (95% CI, 31.907 to 142.025), p = 0.001 | |
| T2 (Discharge) | 36 | 0 | 33.3 | 2.8 | 8.5 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 50 | 2.9 | 10.3 | ||||
| T4 (12 months post-discharge) | 31 | 0 | 50 | 3.2 | 10.9 | ||||
| Pro Re Nate (PRN) medications | Number of medications | T1 (Admission) | 35 | 0 | 2 | 0.6 | 0.7 | F(2.565, 74.392) = 3.604, p = 0.022 | T2-T3 0.367 (95% CI, 0.049 to 0.685), p = 0.017 |
| T2 (Discharge) | 35 | 0 | 3 | 0.8 | 0.8 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.4 | 0.7 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 2 | 0.4 | 0.7 |
| BNF category | Variable | Timepoint | N | Min. | Max. | Mean | SD | Statistically significant changes* | Statistically significant pairwise comparisons |
|---|---|---|---|---|---|---|---|---|---|
| Total regularly prescribed medications | Number of medications | T1 (Admission) | 36 | 0 | 7 | 2.6 | 1.9 | ||
| T2 (Discharge) | 36 | 0 | 6 | 2.3 | 1.4 | ||||
| T3 (6 months post-discharge) | 36 | 0 | 5 | 1.9 | 1.3 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 4 | 1.7 | 1.3 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 378.3 | 127.1 | 98.9 | |||
| T2 (Discharge) | 36 | 0 | 387.5 | 121.2 | 97 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 307.1 | 101.4 | 80.2 | ||||
| T4 (12 months post-discharge) | 30 | 0 | 350 | 90.1 | 102.9 | ||||
| Regularly prescribed antipsychotic medications | Number of medications | T1 (Admission) | 35 | 0 | 3 | 0.7 | 0.8 | ||
| T2 (Discharge) | 36 | 0 | 2 | 0.8 | 0.6 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.8 | 0.6 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 2 | 0.8 | 0.7 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 168.8 | 27.1 | 41.8 | |||
| T2 (Discharge) | 36 | 0 | 143.3 | 38.9 | 37.6 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 141.7 | 33.5 | 37.3 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 140 | 31.7 | 37.9 | ||||
| Regularly prescribed mood stabilising medications | Number of medications | T1 (Admission) | 35 | 0 | 2 | 0.3 | 0.6 | ||
| T2 (Discharge) | 36 | 0 | 2 | 0.1 | 0.4 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.1 | 0.4 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 1 | 0.1 | 0.2 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 100 | 8.1 | 21.9 | |||
| T2 (Discharge) | 36 | 0 | 136 | 5 | 23.1 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 136 | 7.5 | 26.6 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 80 | 3.3 | 14.7 | ||||
| Regularly prescribed antidepressant medications | Number of medications | T1 (Admission) | 35 | 0 | 1 | 0.6 | 0.5 | ||
| T2 (Discharge) | 36 | 0 | 1 | 0.4 | 0.5 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 1 | 0.4 | 0.5 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 1 | 0.4 | 0.5 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 100 | 29.3 | 34.7 | |||
| T2 (Discharge) | 36 | 0 | 100 | 27.8 | 38.7 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 100 | 28.8 | 40.9 | ||||
| T4 (12 months post-discharge) | 31 | 0 | 100 | 23.9 | 37.9 | ||||
| Regularly prescribed anxiolytic and hypnotic medications | Number of medications | T1 (Admission) | 35 | 0 | 2 | 0.9 | 0.8 | T1-T4 0.452 (95% CI, 0.001 to 0.902), | |
| T2 (Discharge) | 36 | 0 | 3 | 0.8 | 0.9 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.6 | 0.7 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 2 | 0.4 | 0.7 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 150 | 51.9 | 56.1 | |||
| T2 (Discharge) | 36 | 0 | 237.5 | 46.7 | 65.2 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 150 | 28.7 | 44 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 200 | 27.9 | 55.8 | ||||
| Other regularly prescribed psychotropic medications | Number of medications | T1 (Admission) | 35 | 0 | 1 | 0.2 | 0.4 | ||
| T2 (Discharge) | 36 | 0 | 1 | 0.1 | 0.3 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 1 | 0.1 | 0.3 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 1 | 0.1 | 0.3 | ||||
| Total % of BNF maximum doses | T1 (Admission) | 35 | 0 | 50 | 5.2 | 12.6 | T1-T4 85.817 (95% CI, 30.80 to 140.834), | ||
| T2 (Discharge) | 36 | 0 | 33.3 | 2.8 | 8.5 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 50 | 2.9 | 10.3 | ||||
| T4 (12 months post-discharge) | 31 | 0 | 50 | 3.2 | 10.9 | ||||
| Pro Re Nate (PRN) medications | Number of medications | T1 (Admission) | 35 | 0 | 2 | 0.6 | 0.7 | T2-T3 0.367 (95% CI, 0.049 to 0.685), | |
| T2 (Discharge) | 35 | 0 | 3 | 0.8 | 0.8 | ||||
| T3 (6 months post-discharge) | 35 | 0 | 2 | 0.4 | 0.7 | ||||
| T4 (12 months post-discharge) | 32 | 0 | 2 | 0.4 | 0.7 |
Notes:
*Repeated measures ANOVA with Greenhouse–Geisser correction.
**Post hoc analysis with Bonferroni adjustment