Table 1

Challenges associated with organ donation and transplantation process

SN.Hindering factorsImplications for organ supplyInfluence on stages of organ transplant supply chainSources
C1Lack of functional organ procurement networkIneffective facilitation of organ sourcing and allocationSourcing and retrievalBeyar (2011), Wood et al. (2022), Stewart (2021), Beard et al. (2006), Ross and Thistlethwaite (2008), Kaze et al. (2018) 
C2Organ transplant regulations are weak or absentConcerns with organ procurement, supply and transplantation governanceSourcing, retrieval, delivery and transplantationUlasi et al. (2020), Hackmann et al. (2022), Weimer (2010), Shroff (2009) 
C3Inadequate information system infrastructureTransparency and management of the organ supply chain are hampered by a lack of available dataSourcing, retrieval, delivery and transplantationChavez et al. (2020), Olu et al. (2019), Kritchanchai et al. (2018), Massie et al. (2014), Howard and Byrne, 2007; Molnar et al. (2015) 
C4Black market for donated organsAlternative donor supply networks that are in direct competition with regulated transplantation programmesSourcingParada-Contzen and Vásquez-Lavín (2019), Bowden (2013), Yoon, (2018), Woan (2007), Morgan et al. (2005), Taylor (2006) 
C5Lack of effective cold-chain systemThe safety/quality of organs will be at risk if cold-chain systems are not effectiveRetrieval and deliverySharma et al. (2021), Fisher et al. (2020), Net et al. (2003), Vreugdenhil et al. (1991), Koizumi et al. (2015) 
C6Lack of effective organ logistics/transport schemeLogistical problems can jeopardise organ transport and transplant equityDeliveryPullen (2019), Michel et al. (2015), Stewart et al. (2016), Wey et al. (2018) 
C7Lack of skilled labourInadequate skills in organ product handling procedures and inventory management techniquesSourcing, retrieval, delivery and transplantationKartoglu and Milstien (2014), Spearman and McCulloch (2014), Naicker et al. (2010) 
C8Organ donor recruitment challengesAn insufficient supply of donors can be attributed to the difficulty of finding new onesSourcingWilliamson et al. (2019), Feeley and Kruegler (2015), Sharif (2012), Noyes et al. (2019) 
C9Difficulties with matching donors and recipientsThe capacity of logistics to deliver organs to the appropriate individual at the right time can be hindered by challenges in pairing donors and recipientsSourcingLewis et al. (2021), Lee et al. (2019), Orens et al. (2006), Matching Donors (2023), (2020)
C10Organ transplant tourismThe high demand for organ transplants would seem to fuel “transplant tourism”Retrieval, delivery and transplantationHindi et al. (2020), Shimazono (2007), Smith (2012), Budiani‐Saberi and Delmonico (2008) 
C11Getting the consent of a potential donorAffect the timely distribution and delivery of organsSourcingAhmad et al. (2019), Salim et al. (2007), Prabhu (2019), Shaw (2018) 

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