Did the study examine costs and effects of the physical intervention?

Did the study involve an appropriate time horizon?

Did the study involve a comparison?

Was the perspective of the study from businesses, corporations or companies?

Were the study population well-described (included persons, socio-demographics)

Was an explanation of alternatives given?

Were other alternatives mentioned?

Was the study randomized?

Were inferences tested with significances?

Was the sample size adequate to the given question?

Were validity, reliability and robustness tested or mentioned in the study? (e.g. through validated instruments or outcomes)

Did the study list direct, indirect and intangible costs?

Was the range of estimated costs broad enough?

Were capital costs and operating costs included?

Were business administrated costs taken into account? (e.g. data from business cost accounting)

Did the study separate adequate outcomes from costs?

Is there any argument for the chosen outcomes?

Were the outcomes accurately measured?

Are any relevant outcomes omitted?

Were the weights of the outcomes explained?

Were the sources clearly identified?

Where market values absent?

Which costs are measured? (marginal costs, average costs, total costs)

Was the discount rate accurate for longtime studies? (2–5% per year)

Was any justification given for the used discount rate(s)?

E.g. Was there any justification for using a specific ICER?

Was there a sensitivity analysis performed (one-way, two-way or net-benefit)?

Were the conclusions of the analysis based on some overall index or ratio?

Were results compared with other relevant studies?

Did the study discuss the generalizability of the results?

Did the study discuss limitation of the used analysis?