Table 1

Risk factors analysis for diabetic vs. no-diabetic mothers or their siblings

Diabetes in mothers or her siblings ɸ (n = 79)
CovariatesCrude analysisAdjusted analysis
cOR (95% CI) p-valueaOR (95% CI) p-value
Degree of maternal grandparents’ consanguinity
Beyond first cousinsReferenceReference
First cousins1.49 (0.60−3.69)4.91 (1.06−22.68)
Degree of parents’ consanguinity
Beyond first cousinsReferenceReference
First cousins0.56 (0.25−1.28)1.33 (0.46−3.86)
Protogenesic interval
12 monthsReferenceReference
18–24 months1.49 (0.81−2.74)3.02 (1.23−7.42) **
30–120 months0.72 (0.31−1.68)1.16 (0.33−4.09)
Hypertension among mother or her siblings
NoReferenceReference
Yes1.95 (1.14−3.33)2.19 (1.04−4.89) *
Mother’s age at marriage
<21 yearsReferenceReference
21–29 years2.08 (0.99−4.34)2.21 (1.08−4.97) *
30–40 years1.19 (0.29−4.76)1.04 (0.24−4.58)
Degree of maternal grandparents’ consanguinity a6.58 (0.89−48.34)
Degree of maternal grandparents’ consanguinity b10.81 (1.64−71.24) *
Degree of maternal grandparents’ consanguinity c10.87 (1.74−67.81) *
Degree of maternal grandparents’ consanguinity d14.87 (2.09−105.51) **
Degree of maternal grandparents’ consanguinity a,b14.48 (1.44−145.28) *
Degree of maternal grandparents’ consanguinity a,c14.56 (1.52−139.01) *
Degree of maternal grandparents’ consanguinity a,d19.91 (1.82−217.87) *

Note(s):a maternal grandparents first cousins adjusted for parents first cousins; b maternal grandparents first cousins adjusted for hypertension in the mother and her siblings; c maternal grandparents first cousins adjusted for mother’s age at marriage between 21 and 29 years; d maternal grandparents first cousins adjusted for protogenesic interval 18–24 months; cOR: crude odds ratio; aOR: adjusted odds ratio; CI: confidence interval, *p < 0.05, **p < 0.01; ɸ: dependent variable

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