Risk factors analysis for diabetic vs. no-diabetic mothers or their siblings
| Diabetes in mothers or her siblings ɸ (n = 79) | ||
|---|---|---|
| Covariates | Crude analysis | Adjusted analysis |
| cOR (95% CI) p-value | aOR (95% CI) p-value | |
| Degree of maternal grandparents’ consanguinity | ||
| Beyond first cousins | Reference | Reference |
| First cousins | 1.49 (0.60−3.69) | 4.91 (1.06−22.68) |
| Degree of parents’ consanguinity | ||
| Beyond first cousins | Reference | Reference |
| First cousins | 0.56 (0.25−1.28) | 1.33 (0.46−3.86) |
| Protogenesic interval | ||
| 12 months | Reference | Reference |
| 18–24 months | 1.49 (0.81−2.74) | 3.02 (1.23−7.42) ** |
| 30–120 months | 0.72 (0.31−1.68) | 1.16 (0.33−4.09) |
| Hypertension among mother or her siblings | ||
| No | Reference | Reference |
| Yes | 1.95 (1.14−3.33) | 2.19 (1.04−4.89) * |
| Mother’s age at marriage | ||
| <21 years | Reference | Reference |
| 21–29 years | 2.08 (0.99−4.34) | 2.21 (1.08−4.97) * |
| 30–40 years | 1.19 (0.29−4.76) | 1.04 (0.24−4.58) |
| Degree of maternal grandparents’ consanguinity a | 6.58 (0.89−48.34) | |
| Degree of maternal grandparents’ consanguinity b | 10.81 (1.64−71.24) * | |
| Degree of maternal grandparents’ consanguinity c | 10.87 (1.74−67.81) * | |
| Degree of maternal grandparents’ consanguinity d | 14.87 (2.09−105.51) ** | |
| Degree of maternal grandparents’ consanguinity a,b | 14.48 (1.44−145.28) * | |
| Degree of maternal grandparents’ consanguinity a,c | 14.56 (1.52−139.01) * | |
| Degree of maternal grandparents’ consanguinity a,d | 19.91 (1.82−217.87) * | |
| Diabetes in mothers or her siblings ɸ ( | ||
|---|---|---|
| Covariates | Crude analysis | Adjusted analysis |
| cOR (95% CI) | aOR (95% CI) | |
| Beyond first cousins | Reference | Reference |
| First cousins | 1.49 (0.60−3.69) | 4.91 (1.06−22.68) |
| Beyond first cousins | Reference | Reference |
| First cousins | 0.56 (0.25−1.28) | 1.33 (0.46−3.86) |
| 12 months | Reference | Reference |
| 18–24 months | 1.49 (0.81−2.74) | 3.02 (1.23−7.42) ** |
| 30–120 months | 0.72 (0.31−1.68) | 1.16 |
| No | Reference | Reference |
| Yes | 1.95 (1.14−3.33) | 2.19 (1.04−4.89) * |
| <21 years | Reference | Reference |
| 21–29 years | 2.08 (0.99−4.34) | 2.21 (1.08−4.97) * |
| 30–40 years | 1.19 (0.29−4.76) | 1.04 (0.24−4.58) |
| Degree of maternal grandparents’ consanguinity a | 6.58 (0.89−48.34) | |
| Degree of maternal grandparents’ consanguinity b | 10.81 (1.64−71.24) * | |
| Degree of maternal grandparents’ consanguinity c | 10.87 (1.74−67.81) * | |
| Degree of maternal grandparents’ consanguinity d | 14.87 (2.09−105.51) ** | |
| Degree of maternal grandparents’ consanguinity a,b | 14.48 (1.44−145.28) * | |
| Degree of maternal grandparents’ consanguinity a,c | 14.56 (1.52−139.01) * | |
| Degree of maternal grandparents’ consanguinity a,d | 19.91 (1.82−217.87) * | |
Note(s): a maternal grandparents first cousins adjusted for parents first cousins; b maternal grandparents first cousins adjusted for hypertension in the mother and her siblings; c maternal grandparents first cousins adjusted for mother’s age at marriage between 21 and 29 years; d maternal grandparents first cousins adjusted for protogenesic interval 18–24 months; cOR: crude odds ratio; aOR: adjusted odds ratio; CI: confidence interval, *p < 0.05, **p < 0.01; ɸ: dependent variable
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