Result of t-test and two-way ANOVA for MMSE, go/no-Go tasks and fNIRS
| Paired t-test | Two way ANOVA | One way ANOVA | Tukey-Kramer | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Measurement items | TG/pre | TG/post | p-value | CG/pre | CG/post | p-value | Pre/post | TG/CG | interaction | TG Pre/TG Post/ CG Pre/CG Post | TG Pre/Post | CG Pre/Post |
| MMSE | ||||||||||||
| Q1 | 4.8 ± 0.4 | 5.0 ± 0.0 | 0.001 | 4.8 ± 0.4 | 4.1 ± 0.6 | 0.01 | NS | 0.001 | 0.001 | 0.001 | 0.01 | 0.01 |
| Q4 | 3.5 ± 2.0 | 4.7 ± 1.1 | 0.001 | 4.7 ± 0.7 | 3.7 ± 1.9 | NS | 0.01 | NS | 0.01 | 0.001 | 0.01 | NS |
| Total | 27.8 ± 2.2 | 29.5 ± 1.2 | 0.001 | 29.0 ± 0.7 | 27.4 ± 1.9 | NS | 0.001 | NS | 0.001 | 0.001 | 0.01 | NS |
| Go/no-go tasks | ||||||||||||
| Error | 1.7 ± 1.4 | 0.8 ± 0.9 | 0.001 | 1.0 ± 2.2 | 1.6 ± 1.4 | NS | 0.01 | NS | 0.05 | 0.05 | 0.01 | NS |
| fNIRS (mol/L cm) | ||||||||||||
| During go task | ||||||||||||
| 5ch | −0.274 ± 1.949 | 1.413 ± 2.139 | 0.001 | 0.753 ± 2.233 | −0.461 ± 3.858 | NS | NS | NS | 0.01 | 0.01 | 0.05 | NS |
| 18ch | −0.619 ± 2.828 | 2.592 ± 3.856 | 0.001 | 2.156 ± 2.216 | 1.380 ± 4.093 | NS | 0.01 | NS | 0.01 | 0.001 | 0.01 | NS |
| During no-go task | ||||||||||||
| 2ch | 0.259 ± 2.372 | −0.234 ± 2.418 | NS | −1.916 ± 2.777 | −0.083 ± 2.385 | NS | NS | 0.0443 | 0.05 | 0.05 | NS | NS |
| 17ch | 0.622 ± 4.190 | −0.562 ± 3.555 | NS | −1.306 ± 2.963 | 0.389 ± 2.446 | NS | NS | NS | 0.05 | NS | NS | NS |
| 39ch | 0.120 ± 4.682 | −1.192 ± 4.073 | NS | −2.374 ± 2.345 | −0.161 ± 2.470 | 0.05 | NS | NS | 0.05 | NS | NS | NS |
| 42ch | −0.273 ± 5.427 | −3.033 ± 4.711 | 0.05 | −1.336 ± 3.332 | 0.140 ± 2.925 | NS | NS | NS | 0.05 | 0.05 | 0.05 | NS |
| Total ch | 0.160 ± 0.430 | −0.765 ± 0.881 | 0.001 | −0.894 ± 0.825 | −0.702 ± 1.200 | NS | 0.001 | 0.001 | 0.001 | 0.001 | 0.01 | NS |
| Paired | Two way ANOVA | One way ANOVA | Tukey-Kramer | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Measurement items | TG/pre | TG/post | CG/pre | CG/post | Pre/post | TG/CG | interaction | TG Pre/TG Post/ | TG Pre/Post | CG Pre/Post | ||
| MMSE | ||||||||||||
| Q1 | 4.8 ± 0.4 | 5.0 ± 0.0 | 0.001 | 4.8 ± 0.4 | 4.1 ± 0.6 | 0.01 | NS | 0.001 | 0.001 | 0.001 | 0.01 | 0.01 |
| Q4 | 3.5 ± 2.0 | 4.7 ± 1.1 | 0.001 | 4.7 ± 0.7 | 3.7 ± 1.9 | NS | 0.01 | NS | 0.01 | 0.001 | 0.01 | NS |
| Total | 27.8 ± 2.2 | 29.5 ± 1.2 | 0.001 | 29.0 ± 0.7 | 27.4 ± 1.9 | NS | 0.001 | NS | 0.001 | 0.001 | 0.01 | NS |
| Go/no-go tasks | ||||||||||||
| Error | 1.7 ± 1.4 | 0.8 ± 0.9 | 0.001 | 1.0 ± 2.2 | 1.6 ± 1.4 | NS | 0.01 | NS | 0.05 | 0.05 | 0.01 | NS |
| fNIRS (mol/L cm) | ||||||||||||
| During go task | ||||||||||||
| 5ch | −0.274 ± 1.949 | 1.413 ± 2.139 | 0.001 | 0.753 ± 2.233 | −0.461 ± 3.858 | NS | NS | NS | 0.01 | 0.01 | 0.05 | NS |
| 18ch | −0.619 ± 2.828 | 2.592 ± 3.856 | 0.001 | 2.156 ± 2.216 | 1.380 ± 4.093 | NS | 0.01 | NS | 0.01 | 0.001 | 0.01 | NS |
| During no-go task | ||||||||||||
| 2ch | 0.259 ± 2.372 | −0.234 ± 2.418 | NS | −1.916 ± 2.777 | −0.083 ± 2.385 | NS | NS | 0.0443 | 0.05 | 0.05 | NS | NS |
| 17ch | 0.622 ± 4.190 | −0.562 ± 3.555 | NS | −1.306 ± 2.963 | 0.389 ± 2.446 | NS | NS | NS | 0.05 | NS | NS | NS |
| 39ch | 0.120 ± 4.682 | −1.192 ± 4.073 | NS | −2.374 ± 2.345 | −0.161 ± 2.470 | 0.05 | NS | NS | 0.05 | NS | NS | NS |
| 42ch | −0.273 ± 5.427 | −3.033 ± 4.711 | 0.05 | −1.336 ± 3.332 | 0.140 ± 2.925 | NS | NS | NS | 0.05 | 0.05 | 0.05 | NS |
| Total ch | 0.160 ± 0.430 | −0.765 ± 0.881 | 0.001 | −0.894 ± 0.825 | −0.702 ± 1.200 | NS | 0.001 | 0.001 | 0.001 | 0.001 | 0.01 | NS |
Notes:
Mean and standard division scores for paired t-test (pre × post), p-value of interaction for two-way ANOVA (pre/post × TG/CG), p-value of inter-group variation for one-way ANOVA (pre/post, TG/CG) and p-value of compare groups for Tukey–Kramer (TG: pre/post, CG: pre/post) of each question in MMSE, go/no-go tasks and fNIRS
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