Figure 1
The flowchart is titled “Identification of studies via databases and registers”, at the top. The flowchart shows four vertical text boxes representing four stages, arranged in a vertical series on the left. From top to bottom, these stages are labeled: “Identification”, “Screening”, “Full-text assessment”, and “Included”. In the “Identification” stage, the first box reads “Records identified from asterisk: PubMed (n equals 6,408) E B S C O C I N A H L (n equals 977)”. A right-pointing arrow leads to another box labeled “Records removed before screening: Duplicates E B S C O C I N A H L removed by Citavi 6 (n equals 927)”. A downward-pointing arrow leads from the first box to the next box labeled “Records screened (n equals 6,458) PubMed (n equals 6,408) E B S C O C I N A H L (n equals 50)” in the “Screening” stage. From this box, a right-pointing arrow arises and points to a text box labeled “Records excluded via screening: PubMed (n equals 6,303)”. From “Records screened (n equals 6,458) PubMed (n equals 6,408) E B S C O C I N A H L (n equals 50)”, a right-pointing arrow arises and points to a box labeled “Reports sought for retrieval (n equals 155) PubMed (n equals 105) E B S C O C I N A H L (n equals 50)” in the same “Screening” stage. From this, two arrows arise and extend rightward and point to two boxes arranged vertically, and the boxes are labeled as follows: “Duplicates PubMed and across PubMed and E B S C O C I N A H L removed by Citavi 6 (n equals 54)” and “Reports not retrieved (n equals 0)”. From “Reports sought for retrieval (n equals 155) PubMed (n equals 105) E B S C O C I N A H L (n equals 50)”, a downward arrow arises and points to a text box labeled “Reports assessed for eligibility (n equals 101) PubMed (n equals 78) E B S C O C I N A H L (n equals 23)” in the “Full-text assessment” stage. From this box, two arrows arise and extend rightward and point to two boxes arranged vertically. The first box at the top is labeled “Reports excluded: (n equals 89) Non-empirical work (n equals 11), Non-European population (n equals 17), Patients in nursing homes (n equals 1), Patients with special care needs (n equals 4), Findings do not fit research interest (n equals 34), Duplicates (n equals 22)”. The second box at the bottom is labeled “Reports excluded due to poor quality (C A S P) (n equals 1)”. From “Reports assessed for eligibility (n equals 101) PubMed (n equals 78) E B S C O C I N A H L (n equals 23)”, a downward arrow arises and points to a text box labeled “Studies included in review (n equals 11)” in the “Included” stage.PRISMA flow diagram