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The COVID-19 pandemic imposed movement restrictions and limited access to modern medical services, prompting the search for alternative solutions, such as indigenous herbal medicines. In Southwest Nigeria, female herbal producers, often with limited economic resources, play a significant role in herbal medicine production. Despite facing multiple challenges, these producers have demonstrated remarkable creativity in navigating the barriers. However, without deliberate efforts to preserve their creative values, indigenous herbal businesses face the threat of extinction. This chapter investigates the resourcefulness of female herbal producers during the COVID-19 pandemic in Southwest Nigeria and proposes strategies for sustaining their trade. Qualitative data were collected to identify the treatment patterns and trade dynamics among female herbal producers in the region. The findings indicate that movement restrictions during the pandemic disrupted herbal producers' access to treatment materials, yet they managed to meet their communities' health needs. These women often serve as first responders and primary healthcare providers in many local communities in Southwest Nigeria, and collaboration with the government will further enhance their effectiveness. The sustainability of indigenous herbal medicine production and trade by women can become a pathway to promote women's economic empowerment in Nigeria if given the necessary support. The chapter concludes with policy recommendations for sustaining the ingenuity of female herbal producers in Nigeria.

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