This study deals with the processes of innovation in the medium technology industrial sectors. First, it illustrates the differences between the linear model of innovation and the systemic and cognitive model of knowledge creation. Then, it focuses on the concepts of connectivity, creativity, and speed of change, which characterize the processes of interactive learning in the industrial clusters. Finally, it illustrates a typology of regions, where problems and policy fields are different, and it indicates the guidelines of a governance of interregional knowledge and innovation networks.

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