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This chapter is a reflection of how Venkataraman’s “The Distinctive Domain of Entrepreneurship Research” has influenced the field of entrepreneurship. The theory underlying the original chapter provided the first true theoretical basis for the discipline of entrepreneurship, grounded in Kirzner and Schumpeter. Its two discrete components, opportunity, and role of the individual became the basis for new approaches in empirical research and new conceptualizations of entrepreneurship theory. These components led to new approaches to concepts such as motivation, perception, and information’s role in the entrepreneurial process. The chapter revisits the three core questions raised by “The Distinctive Domain”: how opportunities arise, why do only some recognize and pursue opportunities, and what are the consequences of the pursuit of opportunities. The chapter concludes with a consideration of the impact of the original chapter in practice and academia.

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