In 2002 when we began reviewing papers for possible inclusion in Advances in Gender Research volume 7: Gender Perspectives on Health and Medicine: Key Themes, and Volume 8: Gender Perspectives on Health and Medicine: Reproduction and Sexuality, the popular press was full of headlines about Hormone Replacement Therapy (HRT) (for references and extended and detailed discussion by researchers and physicians see the editorial by Ronald C. Hamdy, MD, FRCP, FACP (2002) and the letters to the editor (Mikhail, 2003) in the Southern Journal of Medicine).

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