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The problems with cataloguing and categorising heterogeneous resources on the World Wide Web for retrieving precise information are discussed. By providing a database approach to the Web site, these problems can be solved to some extent. The design is done for software in biotechnology and bioengineering. The data about bio software on the Web are collected and arranged in a generalised standard format. These are loaded on to a MYSQL database and are accessed through Practical Extraction and Reporting Language (PERL) script. An attempt has also been made to study the search and memory allocation performance for the following databases: MYSQL, World Wide Web Integrated Set Of Information System (WWWISIS), and Managing Gigabytes (MG).

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