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Purpose

The purpose of this study is to use the method of lines to solve the two-dimensional nonlinear advection–diffusion–reaction equation with variable coefficients.

Design/methodology/approach

The strictly positive definite radial basis functions collocation method together with the decomposition of the interpolation matrix is used to turn the problem into a system of nonlinear first-order differential equations. Then a numerical solution of this system is computed by changing in the classical fourth-order Runge–Kutta method as well.

Findings

Several test problems are provided to confirm the validity and efficiently of the proposed method.

Originality/value

For the first time, some famous examples are solved by using the proposed high-order technique.

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