Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 13, Issue 4

A. Abdel-Latif, R. Bolli, I.M. Tleyjeh, V.M. Montori, E.C. Perin, C.A. Hornung,E.K. Zuba-Surma, M. Al-Mallah, B. DawnArchives of Internal Medicine2007Vol. 167 No. 10pp. 989-997

This well-conducted review assessed the effect of bone marrow-derived cell(BMC) transplantation on cardiovascular outcomes in patients with ischaemic heart disease.The authors concluded that BMC transplantation is associated with modest improvements in physiologic and anatomic parameters compared with conventional therapy, and appears to be safe. These conclusions are likely to be reliable.