Meta-analysis of six-month memantine trials in Alzheimers disease Free

’

Meta-analysis of six-month memantine trials in Alzheimers disease

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 13, Issue 2.

R. Smith Doody, P.N. Tariot, E. Pfeiffer, J.T. Olin and S.M. GrahamAlzheimer’s and Dementia 2007Vol. 3pp. 7-17

This review compared memantine with placebo in the treatment of probable Alzheimer’s disease. The authors concluded that memantine is effective and safe across the spectrum of disease severity. The authors’ conclusions reflect the findings of the review for patients with moderate to severe Alzheimer’s disease and appear reliable. However, benefits were not reported for all outcomes in patients with mild to moderate Alzheimer’s disease.