A systematic review of the effectiveness of strategies for reducing fracture risk in children with juvenile idiopathic arthritis with additional data on long-term risk of fracture and cost of disease management

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 14, Issue 2

J. Thornton, D. Ashcroft, T. O’Neill, R. Elliott, J. Adams et al.,Health Technology Assessment,2008,Vol. 12 No. 3,pp. 1-208

This review, which aimed to assess the effectiveness and safety of bisphosphonates and calcium/vitamin D in children with juvenile idiopathic arthritis and low bone mineral density, concluded that bisphosphonates are a promising treatment, but that better quality research is needed to confirm this. The authors’ conclusions are likely to be reliable.