Benefits and risks of tight glucose control in critically ill adults: a meta-analysis

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 14, Issue 2

R.S. Wiener, D.C. Wiener and R.J. Larson,Journal of the American Medical Association,2008,Vol. 300,pp. 933-944,

Tight glucose control does not significantly reduce hospital mortality among critically ill adult patients, but it does increase the risk of hypoglycaemia. The review was generally well conducted and these conclusions seem likely to be reliable.