Treatment of fibromyalgia syndrome with antidepressants: a metanalysis

Treatment of fibromyalgia syndrome with antidepressants: a metanalysis

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 14, Issue 3

W. Hauser, K. Bernardy, N. Uceyler and C. Sommer,Journal of the American Medical Association,2009,No. 301,pp. 198-209

This review investigated antidepressant treatment for fibromyalgia syndrome(FMS), compared with pharmacological placebo. The authors concluded that treatment with antidepressants for FMS significantly reduced pain, fatigue,sleep disturbances and depression and improved the health-related quality of life (HRQOL). The review was generally well conducted and the conclusion was likely to be reliable.