Systematic review: glucose control and cardiovascular disease in type 2 diabetes

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 15, Issue 1

T.N. Kelly, L.A. Bazzano, V.A. Fonseca, T.K. Thethi, K. Reynolds and J. He,Annals of Internal Medicine,2009,Vol. 151,pp. 394-403

This review found that intensive glucose control reduced the risk for some cardiovascular disease outcomes in patients with type 2 diabetes (e.g. non-fatal myocardial infarction), but did not reduce the risk for cardiovascular death or all-cause mortality, and increased the risk for severe hypoglycaemia. This appeared to be a reasonably well conducted review and the conclusions are likely to be reliable.