B-type natriuretic peptide-guided heart failure therapy
B-type natriuretic peptide-guided heart failure therapy
Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 15, Issue 3
Porapakkham, P., Porapakkham, P., Zimmet, H., Billah, B. and Krum, H,B-type natriuretic peptide-guided heart failure therapy,Archives of Internal Medicine,2010,Vol. 170,pp. 507-514
This review compared the effect of B-type natriuretic peptide (BNP)-guided drug therapy with usual care in patients with chronic heart failure. The authors concluded that BNP-guided therapy reduced all-cause mortality, especially in patients younger than 75 years. This was a reasonably well-conducted review, but the uncertain quality of included trials and concerns regarding generalisability warrant some cautious interpretation.
