Diagnostic value of clinical features at presentation to identify serious infection in children

Diagnostic value of clinical features at presentation to identify serious infection in children

Article Type: Reviews of effectiveness From: Clinical Governance: An International Journal, Volume 15, Issue 4

Van den Bruel, A., Haj-Hassan, T., Thompson, M., Buntinx, F. and Mant, D.,Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review,Lancet,2010,Vol. 375,pp. 834-845

This generally well-conducted review concluded that cyanosis, rapid breathing, poor peripheral perfusion and petechial rash should be used routinely to identify serious infection. Although the conclusions reflect the evidence presented, each clinical feature was assessed in only a few, poor quality,studies. Therefore, the conclusions should be viewed with some caution.