Bioactive-glass (BG)-based resin infiltrants were developed to evaluate their chemo-physico-mechanical properties. Three methacrylate-based experimental resin infiltrants were synthesized using 45S5, fluoridated BG and borosilicate BG (B-BG), whereby pure dimethacrylate resins and Icon were used as a control infiltrants. The degree of conversion (DC), thermal properties and wettability were evaluated. In vitro bioactivity tests and weight measurements were conducted in simulated body fluid for up to 28 days. The optical properties were analyzed in artificial saliva for up to 30 days. The microhardness and morphological changes were investigated following chemical aging. The experimental resin infiltrants displayed a comparable DC and a nearly equivalent wettability to those of Icon. An apatite layer was formed on the surface of experimental samples; however, a non-linear behavior was observed for weight measurement. A reduction in microhardness was observed with chemical aging. The optical properties of experimental infiltrants were better than those of Icon. The B-BG group showed more resistance to chemical aging and showed fewer changes during thermal analysis, as well as less loss of hardness. In contrast to other groups, the 45S5-based group showed a greater in vitro bioactivity. The fluoride (F) and boron (B) ions in BGs showed a positive effect and potential to treat white spot lesions within the confines of this inquiry.
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December 2024
Research Article|
November 28 2024
Physicochemical assessments of ion-doped bioactive-glass-based resin infiltrants Available to Purchase
Syed Zubairuddin Ahmed, BDS, MSc. PFUTL;
Syed Zubairuddin Ahmed, BDS, MSc. PFUTL
Lecturer, Department of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
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Abdul Samad Khan, BDS, MSc, PhD, FHEA;
Abdul Samad Khan, BDS, MSc, PhD, FHEA
Professor, Department of Restorative Dental Sciences, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia (corresponding author: akhan@iau.edu.sa)
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Asma Tufail Shah, MSc, PhD;
Asma Tufail Shah, MSc, PhD
Associate Professor, Interdisciplinary Research Centre in Biomedical Materials, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan
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Budi Aslinie Md Sabri, BDS, MDSc, PhD;
Budi Aslinie Md Sabri, BDS, MDSc, PhD
Associate Professor, College of Dentistry, Universiti Teknologi MARA, Sungai Buloh Selangor, Malaysia
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Arumugam Madhan Kumar, PhD;
Arumugam Madhan Kumar, PhD
Associate Professor, Interdisciplinary Research Center for Advanced Materials, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia
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Sultan Akhtar, MSc, PhD;
Sultan Akhtar, MSc, PhD
Assistant Professor, Department of Biophysics, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
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Mukarram Zubair, MSc, PhD;
Mukarram Zubair, MSc, PhD
Lecturer, Department of Environmental Engineering, College of Engineering, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
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Abbas Saeed Hakeem, MSc, PhD;
Abbas Saeed Hakeem, MSc, PhD
Senior Researcher, Interdisciplinary Research Center for Hydrogen and Energy Storage, King Fahd University of Petroleum and Minerals, Dhahran, Saudi Arabia
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Mohamed Ibrahim Abu Hassan, DSPN, BDS, MDSc, PhD
Mohamed Ibrahim Abu Hassan, DSPN, BDS, MDSc, PhD
Professor, College of Dentistry, Universiti Teknologi MARA, Sungai Buloh Selangor, Malaysia; Professor, College of Dentistry, MAHSA University, Jenjarom, Malaysia
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Publisher: Emerald Publishing
Received:
October 25 2023
Accepted:
June 04 2024
Online ISSN: 2045-9866
Print ISSN: 2045-9858
Emerald Publishing Limited: All rights reserved
2024
Bioinspired, Biomimetic and Nanobiomaterials (2024) 13 (3-4): 45–57.
Article history
Received:
October 25 2023
Accepted:
June 04 2024
Citation
Ahmed SZ, Khan AS, Shah AT, Sabri BAM, Kumar AM, Akhtar S, Zubair M, Hakeem AS, Hassan MIA (2024), "Physicochemical assessments of ion-doped bioactive-glass-based resin infiltrants". Bioinspired, Biomimetic and Nanobiomaterials, Vol. 13 No. 3-4 pp. 45–57, doi: https://doi.org/10.1680/jbibn.23.00069
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