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Metatheory is described as the analysis of the presuppositions of a field of knowledge or practice. The presuppositions at the basis of the practice of information science are discussed, in particular relation to such concepts as information, knowledge (personal and public), message, message designation, information want and need, query, relevance and information search. The nature of these presuppositions is considered, and the conditions under which they may be replaced by others.

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