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Purpose

The COVID-19 crisis has brought to the forefront the importance of rural health enterprises (RHEs), the peculiarity, in these terms, of rural areas, and the impact of rurality on health entrepreneurial activities. This paper aims to undertake a literature review regarding RHEs in the EU, identify research gaps and set future research directions.

Design/methodology/approach

A systematic literature review was conducted and the key aspects coded across four thematic areas – after examining 68 papers.

Findings

The findings reveal that more intense research should be conducted across four area which emerged; rural health providers vs urban health providers; RHEs and rural development; RHEs and quality of life; and social RHEs.

Research limitations/implications

Future research avenues were identified and suggestions for further research on RHEs were provided.

Practical implications

The paper provides insights into how rural areas can attract health enterprises and how health enterprises can operate in rural areas.

Originality/value

This research expands on the limited existing knowledge of RHEs and sets the foundations for further research.

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