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This article examines the issues involved in the treatment with antipsychotic medication of forensic patients with schizophrenia. Poor compliance with medication may lead to a worsening of positive psychotic symptoms and increase the risk of re‐offending. Nurses and other members of the forensic multidisciplinary team spend long periods of time with patients and may form close therapeutic alliances with them. These staff have an important role in helping patients with medication‐related issues, thereby improving treatment outcome.

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