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Large underground spaces are required when constructing multifunctional buildings. These constitute one of the major engineering projects for the World Expo 2010 in Shanghai, China. Restrictions caused by a building’s function, and requirements for arranging municipal pipelines, mean that options for structural systems are limited. This paper presents a scheme design for a large underground space. To achieve a spacious underground passage and to resist the heavy load of the soil that holds pipelines, major structural systems are taken into consideration. Performance criteria for a scheme design involve safety, serviceability and economics. Subsequently, comparisons of a conventional reinforced concrete (RC) system, a prestressed RC system, and a steel–concrete composite (SCC) system are made with regard to these criteria. It is found that a conventional RC structure cannot provide adequate resistance to heavy load at a large column span. Correspondingly, prestressed RC slabs can replace conventional RC structures with the required structural capacity, but suffer drawbacks because construction space is confined. A composite system is desirable for an underground space with a large span and heavy load. Specifically, it has a convenient construction procedure and high economic efficiency which takes advantage of industrial manufacturing of steel members and reduction of concrete formwork.

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