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The attempt to understand the working of the brain suffers from difficulties of definition, since it is not clear that brains can understand brains, and the nature of “understanding” is essentially subjective. If it is accepted that our thought processes are products of evolution, the principles of rational discourse and science are reflections of the environment rather than inherent in us. Nevertheless they are strongly ingrained and well‐founded, but since their implications are essentially subjective they cannot be distinguished from other assertions that would be classed as “mystical”.