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Purpose

This article analyses the new venture creation by patient innovators in 40 countries examining the effects of the four macro-level factors on entrepreneurship, adding a fifth sector-specific (healthcare) factor.

Design/methodology/approach

By applying the statistical tool of principal component analysis, we find a clustering behavior of health user entrepreneurs across countries, indicating that common macro-level conditions affect this phenomenon in a nonlinear way.

Findings

Healthy user innovators are more likely to become entrepreneurs in those countries where creativity, economic opportunities and business environment are increasing from the lower level until a certain threshold. After that level, user entrepreneurship seems to be not relevant.

Originality/value

We contribute to the extant literature about macro-level determinants of entrepreneurship by exploring how much such conditions impact on the decision to create new firm by user innovators.

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