Helicobacter pylori and its role in peptic ulcer disease

The majority of peptic ulcers are associated with Helicobacter pylori infection and it is now clear that eradication of H. pylori dramatically reduces ulcer recurrence. Other important outcomes of H. pylori infection include chronic gastritis (which may be asymptomatic), gastric cancer and lymphoma. Aims to give a brief overview of the discovery, epidemiology, pathophysiology, diagnosis and treatment of H. pylori associated disease.