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Keywords: Drug development
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Teaching Notes
Teaching Notes 1–23.
Published: 20 January 2017
... of prostaglandin when it acts as a vasodilator, a normal physiological reaction. The side effects of Vioxx, therefore, were an unlucky outcome for Merck. Such adverse side effects can never be exactly forecasted at the beginning of drug development, but there is always a risk of discovering them as the research...

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