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Purpose

The purpose of this paper is to study evidence-based records on the impact of some effective nutraceuticals on major depression disorder management; and describe the antidepressant properties of nutraceuticals to achieve health policy targets and maintain a sustainable healthcare system.

Design/methodology/approach

The literature was searched using MEDLINE (PubMed), Google Scholar, PsycINFO and Quertile databases and retrieving relevant published articles in peer-reviewed journals.

Findings

The results provided evidence of a range of nutraceuticals with potential benefits in the management of depression. Studies support the anti-depressant properties of S-adenosyl methionine, folnic acid, 5-hydroxytryptophan and omega-3 fatty acids. The results might represent evidence for an innovative adjunctive neurobiological line for the management and treatment of depression.

Practical implications

Randomized-controlled trials and evaluations continue to provide evidence for the use of nutraceuticals in the treatment of depression.

Social implications

Nutraceuticals emphasize the personalized medicine, which offers a psychophysical balance to the individual.

Originality/value

Nutraceuticals have specific antidepressant properties that may be beneficial in psychiatric populations and reduce pharmacotherapeutic side effects.

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