The primary purpose of this chapter is to synthesize the existing research that describes children who are unresponsive to generally effective early literacy interventions. Studies were selected in which: (a) children ranged from preschoolers to third graders and were at-risk for reading disabilities; (b) treatments targeted early literacy; (c) outcomes reflected reading development; and (d) students’ unresponsiveness to intervention was described. The search yielded 23 studies, eight of which were designed primarily to identify characteristics of unresponsive students; the remaining 15 studies focused on treatment effectiveness, but also identified and described unresponsive students. A majority of unresponsive students had phonological awareness deficits; additional characteristics included phonological retrieval or encoding deficits, low verbal ability, behavior problems, and developmental delays. Methodological issues are discussed that complicate comparisons of non-responders across studies. A secondary purpose of this chapter is to describe findings from recent longitudinal studies that support the hypothesis that non-responders may be the truly reading disabled. Implications for future research and practice are discussed.

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