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Purpose

The aim of this study is to explore which factors of entrepreneurship and innovation influence economic development under the quadruple helix model, contrasting Southern and Northern Europe.

Design/methodology/approach

In this study, secondary data are collected from the Global Entrepreneurship Monitor databases, Organization for Economic Co-operation and Development and Global Competitiveness Index, for four countries in the North and four Southern European countries, for the period from 2007 to 2015. Data was analyzed with SPSS 22.0 software and subjected to several multivariate statistical tests.

Findings

The results show a statistically significant difference in the variables of the four quadruple helix model dimensions. This means that Northern European countries (Finland, the Netherlands, Norway and Sweden) display better results on innovation and entrepreneurship than Southern European countries (Spain, Greece, Italy and Portugal). The results also showed that per capita gross domestic expenditure on R&D is positively related to government and university dimensions, with significant differences between Southern and Northern European countries.

Originality/value

It is hoped that this study will contribute to new evidence on the factors of innovation and entrepreneurship that are decisive for economic development. To the traditional quadruple helix model, control variables were added to meet the endogenous characteristics of the countries.

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