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Significance
Large case numbers, and a new variant with a high case-fatality rate (CFR), have been reported in the region since January. This is the second new clustering (‘clade’) of variants detected in less than ten years, with mpox evolving from a once-uncommon, mostly animal-to-human-transmitted infection with a low CFR to a rapidly spreading, high-impact, human pathogen.
Impacts
International travel, tourism and relations with mpox-endemic countries may be affected.
Without investment in poxvirus research, other disease-causing poxviruses in humans could emerge.
Over the long term, poxvirus vaccines will likely be reintroduced into childhood vaccination schedules.
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2024
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