– The aim of this study was to evaluate anti-bacterial anti-fungal activity of six Lamiaceae family coleus plants based on their traditional uses (breast-milk stimulants) from two Asian countries (Malaysia and Indonesia).
– Plants leaves of coleus species were collected from Kuantan (Malaysia) and Jakarta (Indonesia). From Kuantan, Coleus aromaticus – Malaysia (CATM), Pogostemon cablin – Malaysia (PCM), Coleus blumei-purple leaves – Malaysia (CBPM), Coleus blumei-red leaves – Malaysia (CBRM), Coleus amboinicus – Malaysia (CALM) and from Jakarta Coleus amboinicus – Indonesia (CALI) were collected freeze dried and extracted with aqueous methanol. The antimicrobial activity of the extract was determined by making use of macro dilution and disc diffusion methods. The selected bacteria and fungus used were namely Bacillus subtilis and Staphylococcus aureus (gram positive) and Escherichia coli and Pseudomonas aeruginosa (gram negative) and Candida albicans (a fungi).
– All leaf extracts showed activity at least against one strain of bacteria and the result shows that there were significant differences (p<0.05) between the activities on microorganism. The minimum inhibitory concentration of all leaves extracts ranged from 1.0 to 2.0 mg/ml in inhibiting the growth of S. aureus, E. coli, P. aeruginosa and B. subtilis. This study shows that the coleus plants leaves can be used as anti-bacterial anti-fungal agent apart from the breast-milk stimulation properties.
– This research was carried out with a limited grant and it was not possible to study some more aspects, for example, the composition and the active components isolation, etc. Furthermore, to establish the relationship among the components and bacteria or fungus, etc.
– This research would have greater impact since the leaves of coleus plants are already in use in some communities for the purpose of breast-milk stimulation and insect bite therapy and many more.
– This research takes into consideration the effect of coleus plants on a few bacteria and a fungus which have never been studied before.
