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The impact of technological and organizational changes on strategies, structures, criteria of success, leadership styles, work relations and role interactions has complex and contradictory consequences for today′s work environment. Considers all the potential and interacting stressors in working life and personal living conditions, within the framework of the biographical background and relevant experiences of subjects, in order to understand and explain the multifactoral pathogenesis of mental stress and its many side‐effects. Pursues this integrated consideration through an interdisciplinary approach, involving psychiatry and mental hygiene, organizational psychology and occupational medicine. Research is carried out on a sample of 292 subjects – male and female managers – the basic framework being an epidemiological approach, both descriptive(study of distribution) and analytical (study of determinants), which uses medical anamnesis, biographical questionnaire and psychiatric interview.

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