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This study investigates the occupational stress amongst 355 male and female Greek junior hospital doctors (JHDs) working in the Greater Athens area. The initial phase of the research involved in‐depth interviews with a random stratified sample of sixty JHDs, both male and female, in a variety of specialties of junior hospital staff. An extended version of the occupational stress indicator (OSI) questionnaire was developed, incorporating additional items based on the results of the qualitative part of the study, and on previous research findings in the same area. The sample consisted of 193 males and 162 females JHDs, who completed the OSI. Analyses of the data demonstrated that, overall, JHDs presented significantly higher levels of sources of pressure than the normative population and other comparative occupational samples. As regards the various sub‐group comparisons, bivariate analyses revealed that there were significant differences between male and female JHDs in certain aspects of pressure (“career and achievement” and “home/work interface”). Multivariate analyses revealed that predictors of physical and mental ill health and job dissatisfaction were type A behaviour and “demands of the profession” respectively. The research implications of the findings are discussed.

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