SIMULATION OF DRUG EFFECTS IN THE CENTRAL NERVOUS SYSTEM Available to Purchase

Pharmacological experiments involving the determination of sites of action and mode of action of drugs in the central nervous system provide results which may be difficult to interpret with certainty. Difficulties arise mainly from the highly complex, interactive nature of the system under study. Despite gross simplifications the problems still present serious limitations to the use which can be made of the results. A computer simulation is described which, given information defining the possible structure of the system under investigation, the drug effects and experimental factors, will provide information relating to changes in behaviour of the system.