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The development of a sensor microsystems containing all the components of data acquisition system, such as sensors, signal‐conditioning circuits, analog‐digital converter, interface circuits and embedded microcontroller (MCU), has become the focus of attention in many biomedical applications. A review of the microsystems technology is presented in this paper, along with a discussion of the recent trends and challenges associated with its developments. A basic description of each sub‐system is also given. This includes the different front end, mixed analog‐digital, power management, and radio transmitter‐receiver circuits. These sub‐system designs are presented and discussed in a comparative study and final remarks are made. The performance of each sub‐system is assessed regarding many aspects related to the overall system performance.

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